Genetics – Molecular basis of inheritance MCQs 2


Question #1: If the sequence of nucleotide on m-RNA is HO- AUGCUGGCAUCUGUA-P, where P-represents phosphate radical and (OH)-hydroxyl radical, in which direction translation will occur?

Question #2: Fragment of DNA contains 31 residues of thymine and 46 residues of guanine. The number of hydrogen bonds between complementary strands and the number of complete twists through 360° will respectively be

Question #3: Match the description in List I with the nucleic acids in List II. Use the codes below: List I List II 1. mRNA (i) 3’ACCTG 5′ 2. DNA (ii) contained in ribosomes 3. tRNA (iii) approximately 80 nucleotides long 4. rRNA (iv) forms a template for the synthesis of polypeptide chains

Question #4: In DNA synthesis, DNA polymerases (DP) face several restrictions. ONE of them is incorrect,

Question #5: A small piece of yeast DNA reads as – 5′ TCGATCGAAGGG 3′. One of the following represent the sequence of mRNA which is transcribed from the complementary strand as a template.

Question #6: In a synthetic DNA template, every third purine base is replaced by another purine and pyrimidine by another pyrimidine. The resultant gene will code for a protein that is

Question #7: Choose the answer that has the following events of protein synthesis in the proper sequence. i ) an aminoacyl-tRNA binds to the A site. ii ) a peptide bond forms. Iii) tRNA leaves the P site and the P site remains vacant iv ) small ribosomal subunit associates with mRNA v ) translocation of the tRNA to the P site.

Question #8: In a charged transfer RNA, the nucleotide bound to the amino acid is adenosine (A), and the next two nucleotides are cytidine (C). What can you tell about the DNA codon to which this transfer RNA corresponds?

Question #9: If 35% of the bases of a DNA molecule are thymine, it follows that it also contains:

Question #10: Following are some statements regarding replication of a DNA and transcription. i. During the replication even the introns are replicated whereas introns are not transcribed during the process of transcription. ii. Some of the bases that are incorporated during replication differ from those that are incorporated during transcription. iii. There is no need of unwinding of strands during transcription whereas replication process needs the unwinding of DNA strands. iv. DNA-RNA hybrid is formed at some stage during both the processes. The correct statements are:


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