Enzyme Classification – Mnemonic

Enzyme Classification

Over The HILL

Oxidoreductases
Transferases
Hydrolases
Isomerases
Ligases
Lyases

 

 

Classification of enzymes:

1).Oxidoreductases: catalyzes the transfer of hydrogen or oxygen atom or electrons from one substrate to the other. (Redox reactions).
E.g., Oxidases, Dehydrogenases, Oxygenases, Peroxidases, Catalases.

oxidoreductase

2).Transferases: catalyzes the transfer of a functional group from one substrate to the other.
E.g., Kinases, Transaminase.

transferase

 

3).Hydrolases: catalyzes hydrolysis or breakdown of the substrate.
E.g., Esterase, digestive enzymes, lysozyme, acid phosphatase.

hydrolases

4).Isomerases: catalyzes intramolecular changes in the substrate.
E.g., Isomerase, Fumarase.

isomerase

 

5).Lyases: catalyzes the non-hydrolytic removal of a group or addition of a group to a substrate.
E.g., Decarboxylases, Aldolases.

lyases

6).Ligases (Synthetases): catalyzes joining of two molecules by forming new bonds.
E.g., Citric acid synthetase.

ligases

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